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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WWOX
All Species:
14.24
Human Site:
S278
Identified Species:
24.1
UniProt:
Q9NZC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZC7
NP_057457.1
414
46677
S278
S
L
G
K
L
D
F
S
R
L
S
P
T
K
N
Chimpanzee
Pan troglodytes
XP_001144696
363
41022
T228
T
K
D
G
L
E
T
T
F
Q
V
N
H
L
G
Rhesus Macaque
Macaca mulatta
XP_001105944
398
45056
H263
I
V
V
S
S
E
S
H
R
F
T
D
I
N
D
Dog
Lupus familis
XP_852623
383
43043
C248
Q
L
L
Q
D
V
L
C
R
S
A
P
A
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91WL8
414
46494
S278
S
S
G
K
L
D
L
S
R
L
S
P
P
R
S
Rat
Rattus norvegicus
NP_001099658
356
40173
T221
F
A
L
P
W
S
L
T
K
D
G
L
E
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505354
146
16628
T10
T
S
F
N
S
V
S
T
Q
F
I
A
A
L
T
Chicken
Gallus gallus
Q5F389
414
46711
S278
S
S
G
K
L
D
F
S
L
L
S
P
S
K
K
Frog
Xenopus laevis
NP_001088080
143
16305
G8
M
A
A
L
K
Y
A
G
L
D
D
T
D
S
E
Zebra Danio
Brachydanio rerio
Q803A8
412
46303
D275
S
C
G
N
L
D
L
D
L
L
S
P
P
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLU5
409
46492
H273
P
V
E
N
L
A
V
H
H
L
S
P
P
P
E
Honey Bee
Apis mellifera
XP_395282
414
46992
H271
L
R
T
V
E
D
F
H
Q
L
S
L
S
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789399
410
45991
S274
Y
S
N
K
L
D
L
S
E
V
A
M
P
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42536
405
43844
S266
G
L
N
G
L
N
S
S
A
M
I
D
G
G
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
84.7
82.8
N.A.
93.7
81.1
N.A.
26
83
29.2
71.9
N.A.
48.3
51.2
N.A.
56.2
Protein Similarity:
100
86.2
88.4
87.4
N.A.
96.1
83.8
N.A.
29.4
93
33.3
84.3
N.A.
65.2
66.6
N.A.
73.4
P-Site Identity:
100
6.6
6.6
20
N.A.
66.6
0
N.A.
0
73.3
0
46.6
N.A.
26.6
26.6
N.A.
33.3
P-Site Similarity:
100
26.6
33.3
40
N.A.
80
13.3
N.A.
20
80
0
53.3
N.A.
33.3
40
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
0
0
8
8
0
8
0
15
8
15
0
0
% A
% Cys:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
43
0
8
0
15
8
15
8
0
22
% D
% Glu:
0
0
8
0
8
15
0
0
8
0
0
0
8
0
15
% E
% Phe:
8
0
8
0
0
0
22
0
8
15
0
0
0
0
0
% F
% Gly:
8
0
29
15
0
0
0
8
0
0
8
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
22
8
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
15
0
8
0
0
% I
% Lys:
0
8
0
29
8
0
0
0
8
0
0
0
0
22
15
% K
% Leu:
8
22
15
8
58
0
36
0
22
43
0
15
0
15
0
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
15
22
0
8
0
0
0
0
0
8
0
8
8
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
0
43
29
15
8
% P
% Gln:
8
0
0
8
0
0
0
0
15
8
0
0
0
8
0
% Q
% Arg:
0
8
0
0
0
0
0
0
29
0
0
0
0
15
0
% R
% Ser:
29
29
0
8
15
8
22
36
0
8
43
0
15
8
8
% S
% Thr:
15
0
8
0
0
0
8
22
0
0
8
8
8
8
15
% T
% Val:
0
15
8
8
0
15
8
0
0
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _